|Definition||Down syndrome is a genetic disease caused by an abnormality of chromosome 21, which manifests itself in the form of mental retardation, heart defects and developmental disorders.|
|History||The syndrome was clinically described in 1866 by John Langdon Down. Already in the early 1930s, it was recognized that the cause of the syndrome could be chromosomal abnormalities. In 1959, it was found that most children with Down syndrome have 47 chromosomes, an additional element is a small acrocentric chromosome, identified as chromosome 21.|
|Symptoms||The development of children with Down syndrome is usually slower than normal. They begin to sit, crawl and walk about twice as late as children with normal development. Patients also have a moderate degree of mental retardation.|
|Causes||The cause of Down’s disease is an anomaly of the 21st chromosome, which is characterized by the presence of copies of genetic material on the 21st chromosome in the form of a trisomy or translocation. The 21st chromosome affects almost all organ systems and is responsible for the traits and developmental features that are impaired in Down’s disease.|
|Prevention||Prevention of the birth of children with Down syndrome has not been developed. People who are at risk for having a child with this disease are recommended to undergo a genetic study during pregnancy planning.|
|Diagnostic Method||The diagnosis is made on the basis of a characteristic clinical picture. Newborns are tested for Down syndrome. Pregnant women are also assigned studies aimed at identifying Down syndrome in the fetus. Down syndrome is suspected based on the presence of appearance features characteristic of this disease. The diagnosis is confirmed by karyotyping – a study of the child’s chromosomes for abnormalities.|
|Treatment||Treatment depends on the manifestations of the disease. Although it is impossible to cure the syndrome itself, working with a defectologist from an early age contributes to the development of the child’s mental functions.|
|Duration||Down syndrome is a lifelong disease, and cannot be cured.|
|Prognosis||Early initiation of treatment will maximize the development of the abilities of children with Down syndrome and improve their quality of life.|
|Complications||Children with Down syndrome may experience the following complications: heart defects, leukemia, infectious diseases, dementia, sleep apnea, and obesity.|
|Frequency in Population||The estimated incidence of Down syndrome is between 1 in 1,000 to 1 in 1,100 live births worldwide, according to the WHO.|
|Deaths||At the turn of the 20th century, children with Down syndrome rarely lived past 9 years old. Now, due to advancements in treatment, the majority of people with the condition will live to age 60.|
|Society||Nowadays, society becomes increasingly more inclusive towards people with Down syndrome, providing them with jobs and better social support.|
📝 Down Syndrome Research Papers Examples
- Down Syndrome General AnalysisThis case-report will focus on the role of the aforementioned factors in the current status of Down syndrome, followed by the possible laboratory testing of the disease.
- Down Syndrome: History and TreatmentDown syndrome remains one of the most commonly diagnosed genetic diseases in modern practice. One of the lifelong chronic intellectual disabilities, Down syndrome, develops due to genetic modification.
🏆 Best Down Syndrome Essay Titles
- The Causes, Symptoms, Diagnosis, and Management of Down Syndrome
- Problems Associated With Children With Down Syndrome
- The Physical and Mental Characteristics of Children with Down Syndrome, Increased Risk Factors, and the Need for Medical Care and Stimulating Environments
- Evolution of Neuroinflammation Across the Lifespan of Individuals With Down Syndrome
- Corrigendum: Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells
- The Characteristics and Issue of Down Syndrome
- The Negative and Positive Influence of the Media on People with Down Syndrome
- Analysis of Complementary Medicine Use by Parents for Children With Down Syndrome
- The Effects Down syndrome has on Motor Skills
- Parents and Children with Birth Defects: Down Syndrome
- Microstate Changes Associated With Alzheimer’s Disease in Persons With Down Syndrome
- Psychological Support for Young Adults with Down Syndrome: Dohsa-Hou Program for Maladaptive Behaviors and Internalizing Problems
- Improving Working Memory Abilities in Individuals With Down Syndrome
- Benefits and Harms of Mammography Screening for Women With Down Syndrome
- Validating the Cognitive Scale for Down Syndrome (CS-DS) to Detect Longitudinal Cognitive Decline in Adults With Down Syndrome
- Psychological And Physical Characteristics Of Down Syndrome
- The Prevalence, Causes and Impact of the Down Syndrome in the United States
- The Causes, Effects, and Awareness Regarding Down Syndrome
- Oral Care For Autistic And Down Syndrome Patients
- New Approaches to Studying Early Brain Development in Down Syndrome
- Down Syndrome and the Formation Of Reproductive Cells
- Learning Styles For Children With Down Syndrome
- Genetics and Evolution: Cystic Fibrosis and Down Syndrome
- Reliability of Informant-Report Measures of Executive Functioning in Children With Down Syndrome
- Sign Language with Toddlers with Down Syndrome
- Parent‐Mediated Interventions for Promoting Communication and Language Development in Young Children With Down Syndrome
- Neuro-Ophthalmological Manifestations in Children with Down Syndrome: Current Perspectives
- The Causes and Physical and Mental Effects of Down Syndrome
- Dance Therapy for Down Syndrome Effects and Improvements
- Psychometric Properties and Predictive Value of a Screening Questionnaire for Obstructive Sleep Apnea in Young Children With Down Syndrome
- Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells
- Comparing the Differences Between Down Syndrome and Autism
- Metabolic and Vascular Imaging Biomarkers in Down Syndrome
- The Amniocentesis and the Abnormalities for the Down Syndrome
- Autism, Down Syndrome and Equal Rights: A Look at the Past and Present of Diverse Populations and Sport
- Rodent Models in Down Syndrome Research: Impact and Future Opportunities
- Cognitive Skills, Behavior and Learning Potential of Preschool Children with Down Syndrome
- The Speech and Language Deficits of Children With Down Syndrome
- Development and Learning For People WIth Down Syndrome
- The Social Issues, Educational Importance, Historical Research, and Current Trends of Teaching Students with Down Syndrome
❓ Down Syndrome Research Questions
- Does Tonsillectomy Increase Obesity Risk in Children With Down Syndrome?
- How Many Babies Are Born With Down Syndrome?
- What Is the Cause of Down Syndrome?
- What Is the Population of People With Down Syndrome?
- What Should You Know About People With Down Syndrome in the U.S.?
- How Do Medical Issues and Care Affect People With Down Syndrome?
- How Will a Baby With Down Syndrome Affect Family?
- What Is the Future for a Person With Down Syndrome in the U.S.?
- Is There a Cure for Down Syndrome?
- How Can Parents and Providers Help Teens and Young Adults With Down Syndrome Transition Into Adulthood?
- What Are the Health Issues for Adults With Down Syndrome?
- How Does Down Syndrome Affect Your Health?
- How Does Mosaicism Happen in Down Syndrome?
- When Was Down Syndrome Discovered?
- What Is the Likelihood of Having a Child With Down Syndrome?
- What Impact Does Down Syndrome Have on Society?
- What Are Levels or Degrees of Down Syndrome?
- Do People With Down Syndrome All Look Alike?
- Can People With Down Syndrome Live Independently?
- How Long Are People With Down Syndrome Expected to Live?