Seizure and Prescribed Medication Analysis

Seizure is a condition in which the action of the nerves in the human brain is interfered with, leading to illness. The commonly used class of drugs include antiepileptic drugs (AEDs). These comprise brivaracetam (also known as briviact), carbamazepine (Tegretol), and clobazam (Frisium) (Brodie, 2017). Firstly, briviact is known to treat seizures because of the anti-convulsing action due to the increased discerning similarity for the synaptic vesicle protein present in the system. It has a major role in controlling and regulating neurotransmission through activation of vesicle combinations and maintaining reserves. It is directed for the treatment and prevention of partial inception of seizure victims of four years. Briviact is engrossed into the body and enters the brain faster, and it can exhibit less interaction with other medications. Briviact is highly processed by hydrolysis through amidase enzymes into an inactive form for removal.

Moreover, carbamazepine helps in the prevention and control of seizures and relieves body pain. It is a sodium blocker that muddles especially to voltage-controlled sodium networks in their passive forms. It inhibits the recurring and continued firing of an action perspective. The indications are purely and specific for partial seizures, which have multifaceted symptomatology and integrated seizure patterns and sequences. A single dosage of the medication is absorbed completely and it is dispersed slowly as it enters the central nervous system due to its high solubility rate. It is processed through oxidation before it is eliminated in urine. It is an effective inducer of hepatic 3A4 in the system and decreases the plasma levels of other medications mainly processed by 3A4 through metabolic induction.

Clobazam is a seizure treatment drug that is synthesised in the liver into parent form. Frisium enables many of the brain activities to stop the disorder. It provides the brain with electrical stability as a result of post-synaptic inhibitory action. The dug indication is complex partial and lack of seizures also efficient in controlling the negligible motor actions of young kids. The drug is absorbed at a higher rate in the blood system and take an average time of three hours after intake. The increased volumes of distribution indicate that high clobazam content is present in the tissues. T is processed in the liver through N-desmethylclobazam and 4-hydroxyclobazam actions. Norclobazon is an enzyme that simplifies the action of N-demethylation in the CYP2C19 together with CYP2B6, and it is eliminated through urine.


Brodie, M. (2017). Tolerability and safety of commonly used antiepileptic drugs in adolescents and adults: A Clinician’s Overview. CNS Drugs, 31(2), 135-147.

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NursingBird. 2023. "Seizure and Prescribed Medication Analysis." March 7, 2023.

1. NursingBird. "Seizure and Prescribed Medication Analysis." March 7, 2023.


NursingBird. "Seizure and Prescribed Medication Analysis." March 7, 2023.