Atherosclerosis: Pathophysiology and Treatment

Atherosclerosis is one of the chronic conditions and killer diseases across the globe. The main symptom of the disease is hardening of heart arteries due to lipid accumulation. Even though the disease’s leading cause is unknown, research studies indicate that predisposing factors include cigarette smoking, diabetes, and genetic abnormalities (Bergheanu et al., 2017).

In this case, the possible leading cause of Mr. K’s disease could be due high cholesterol, inactivity, and chronic overweight. The increased lipid levels may have resulted in the changes in the arterial endothelial permeability which may have allowed the migration of lipids and other particles in the arterial wall. Cigarette smoking must have resulted in increased dirt and stiffness of the arteries, thus, causing the disease (Bergheanu et al., 2017). All these negative factors have a high level of susceptibility to atherosclerosis.

Research studies continues to suggest that a number of complications may emerge as a result of the disease. The patient may experience intermittent chest pain or angina, sudden numbness or weakness, and temporary loss of vision (Bergheanu et al., 2017). In some cases, the patient may experience slurred speech and transient ischemic attack. In severe cases, Mr. K may continue to develop high blood pressure, leg pain, and drooping in the face muscles. Therefore, it is essential to take care of all these signs to ensure that the patient’s condition does not deteriorate.

In conclusion, early diagnosis and treatment are some of the major approaches which can help prevent the progress of the condition. The use of analgesic drugs and improved lifestyle plans play a critical role in reducing the overall progress of the disease. Simple aerobic exercises, coupled with an improved diet, will help promote the blood’s free circulation and the burning of the lipids and fats in the heart region.


Bergheanu, S. C., Bodde, M. C., & Jukema, J. W. (2017). Pathophysiology and treatment of atherosclerosis. Netherlands Heart Journal, 25(4), 231-242. Web.

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1. NursingBird. "Atherosclerosis: Pathophysiology and Treatment." May 12, 2022.


NursingBird. "Atherosclerosis: Pathophysiology and Treatment." May 12, 2022.